Gorlin-Goltz-Syndrom – nicht nur ein Syndrom maligner Lidtumoren

Rachel Carson Syndrom

For years some ecologists have been convinced that pesticides are contributing to a decline in amphibian species around the globe. From an apparent epidemic of deformed frogs in Minnesota to the near disappearance of yellow-legged frogs from California’s Sierra Nevada Mountains, pesticides have been considered prime suspects. This suspicion is no doubt rooted in the belief by the ecological com...

Das Hepatopulmonale Syndrom

Gorlin-Goltz Syndrome

The Gorlin-Goltz syndrome (GGS) (the nevoid basal cell carcinoma syndrome-NBCCS) is a rare autosomal dominant syndrome caused due to mutations in the PTCH (patched) gene found on chromosome arm 9q. The syndrome, characterized by increased predisposition to develop basal cell carcinoma and associated multiorgan anomalies, has a high level of penetrance and variable expressiveness. GGS is a multi...

Gorlin-Goltz syndrome.

Gorlin-Goltz syndrome is a rare multisystemic disease inherited in an autosomal dominant pattern. It is characterized by numerous basal cell carcinoma of the skin, jaw cysts, and skeletal anomalies such as frontal bossing, vertebral anomalies, palmoplantar pits, and falx cerebri calcification. There is a tendency to tumors including medullablastoma, fibroma, rabdomyoma, leiomyosarcoma etc.. The...

Gorlin-Goltz Syndrome

The Gorlin-Goltz syndrome (GGS) (the nevoid basal cell carcinoma syndrome) is a rare autosomal dominant syndrome caused due to mutations in the patched gene found on chromosome arm 9 q. It shows high penetrance and variable expressivity; is characterized by basal cell carcinomas, odontogenic keratocysts, palmar and/or plantar pits and ectopic calcifications of the falx cerebri. Until date, very...